Criminal Minds: "Penelope" The team unites to determine if Garcia's life is being threatened by a serial killer. Nicholas Brendon guest stars. Criminal Minds starring: Kirsten Vangsness, Joe Mantegna, Thomas Gibson, Shemar Moore, Matthew Gray Gubler, A.J. Cook and Paget Brewster. Wednesday, November 21 (9:00-10:00 PM, ET/PT). Episode info courtesy of cbs.com